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Product
Information
Exudate is a normal feature of wound healing produced in the inflammatory and
proliferative phases, but exudate form chronic non-healing wounds can have a deleterious
effect on the activity of certain cells and growth factors involved in the healing
cascade. It contains a significant number of growth inhibitory agents such as
matrix metalloproteinases, which if they remain in direct contact with the wound
(as is the case with more typical interactive dressings) will in fact
inhibit healing. In a study by Bucalo, Eaglestein and Falanga chronic wound fluid
was shown to inhibit the proliferation of human dermal fibroblasts and failed
to stimulate the proliferation of microvascular endothelial cells and keratinocytes
(3). In addition, wound exudate increases
the risk of infection if it strikes through primary and secondary dressings and
can be a portal for the access of pathogens. Hence the retention of exudate close
to the wound surface can limit the usefulness of occlusive dressings in chronic
wounds. |
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How to order
Kerraboot is available on prescription and listed in the Drug Tarriff part IXA.
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 Usage
Guidelines
Full instructions on how to correctly
apply Kerraboot and how often it should be changed as well as a detailed application
protocol. ......read more
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